English dictionary annihilate meaning and definition Definition and meaning of annihilate at MeaningMonkey.org. annihilate meaning and definition in the English Dictionary. ANNIHILATE verbDefinition of annihilate (verb)kill in large numbers"the plague wiped out an entire population"synonyms: carry off, decimate, eliminate, eradicate, extinguish, wipe out Source: Princeton University Wordnet
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